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"It's a tremendous leap of faith for young investigators to commit themselves to translational research. It takes a special sort of person; you have to be willing to take risks." –Anthony Hayward, NIH National Center for Research Resources

"The opportunity for this career development is now. I think the job opportunities that follow on that will be very substantial." -Graham Lord, King's College London and Guy's and St. Thomas' hospitals

"The best and the brightest seem not to be going into science as much as they did in the past." And those who do opt for research careers "seem to be dropping out at a very high rate." --Mark Donowitz

Fewer faculty jobs are tenure-track, but job seekers in academic medical research need to look beyond the tenure-track label.

Electronic patient data and research repositories mean new opportunities in medical informatics.

Recovery Act funding will give a boost to a field focused on containing health care costs while maintaining quality.

Despite layoffs, pharmaceutical companies are hiring researchers to strengthen their early drug-development programs.

Regulations at every step of drug development mean jobs for regulatory scientists at every step, too.

It was a difficult year for careers in science but another good year for Science Careers.

Science Careers presents articles on clinical and translational science careers, produced with generous support from the Burroughs Wellcome Fund.