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State Key Laboratory of Reproductive Medicine (SKLRM)

Established in 2011 in Nanjing, Jiangsu province, China, the State Key Laboratory of Reproductive Medicine (SKLRM) is a Chinese Ministry of Science and Technology designated national center for research on reproductive medicine. Its predecessor, the Laboratory of Reproductive Medicine of Jiangsu Province was founded in 1997, and promoted to the Ministry-Province Jointly-Constructed cultivation Base for State Key Laboratory in 2004. The lab has undergone rapid development and further expansion since, which help to land the honor being selected as one of the State Key Laboratories.

SKLRM is housed in Nanjing Medical University, a historic yet vibrant school. In 2011 Nature Publishing Index Nanjing Medical University was ranked among the top 20 Chinese Universities (15th in China and 53rd in the Asia and Pacific region).

Currently, SKLRM has 88 staff members, including 46 professors, 12 associate professors, and 13 assistant professors as well as technicians and administrators. The current director, Professor Jiahao Sha, is a long-time researcher in the field of spermatogenesis and male infertility and has been recognized for his work on genomics/proteomics work on spermatogenesis and GWAS studies on azoospermia patients. The faculty of SKLRM includes one member of Chinese Engineering Academy; one Yangste Scholar Professor of the Chinese Ministry of Education (CAE); six winners of National Outstanding Youth Fund; two recipients of the "Thousand People Plan;" and three candidates for "The State Candidate of Millions of Talents Project in the New Century". In addition, three of its professors served as the chief scientist for a number of National 973 projects and five professors have led Key Projects from National Natural Science Foundation of China as principal investigators. In 2006, the research team of SKLRM has also been selected as Yangtse River Scholar Innovation Team, CAE. A salient feature of SKLRM is its multidisciplinary approach to research. The SKLRM investigators represent a variety of different disciplines including Obstetrics and Gynaecology, Andrology, Histology, Embryology, Pathology, Immunology, Toxicology, Biochemistry, and Molecular Epidemiology. The extensive interactions and close collaborations among them have sparked novel ideas and new approaches in reproductive research.

SKLRM possess one of the best facilities for reproductive medicine in the nation, with more than 4,000 square meters of research space, and over 600 square meters of space for diagnosis and treatment of clinical reproductive defects. The laboratory is concerned with key problems of human reproductive health. The main research directions include: (1) Molecular mechanisms underlying gametogenesis defects; (2) Environment-gene interaction effects on gametogenesis; (3) Assisted reproductive technologies and the health of its offspring; (4) Molecular mechanisms of reproduction-related diseases (including the cancers of reproductive system, birth defects, metabolic disorders and reproductive defects); and (5) Regulation of reproductive hormone on the target organs. Via intramural and extramural collaboration, SKLRM members work cooperatively in addressing major questions in these research directions. The school has hosted researchers in reproductive medicine from various countries and participated actively in conferences held overseas and at home. Recently SKLRM has established a long-term, broad-based cooperation with State Key Laboratory of Reproductive Biology (SKLRB), Chinese Academy of Science (CAS). Our research findings have been published in high-impact journals including Nature Genetics, Nature Medicine, The Lancet, Proceedings of the National Academy of Sciences, Plos Genetics, American Journal of Human Genetics, and Human Reproduction.

In the future, we hope to continue to address clinical reproductive health-related issues, to further strengthen the integration of basic and clinical research, to vigorously promote the translation of basic research finding, to make concrete contributions to improve the life quality and the reproductive health of human being.

SKLRM is undergoing an unprecedented expansion and development, with many opportunities and challenges for its members. The recruitment is ongoing; we welcome talents in any areas of reproductive medicine research. The details of recruitment can be found in ScienceCareers.

http://sklrm.njmu.edu.cn/